| Title |
Application of polydopamine functionalized zinc oxide for glucose biosensor design / |
| Authors |
Fedorenko, Viktoriia ; Damberga, Daina ; Grundsteins, Karlis ; Ramanavičius, Arūnas ; Ramanavičius, Simonas ; Coy, Emerson ; Iatsunskyi, Igor ; Viter, Roman |
| DOI |
10.3390/polym13172918 |
| Full Text |
|
| Is Part of |
Polymers.. Basel : MDPI. 2021, vol. 13, iss. 17, art. no. 2918, p. [1-8].. eISSN 2073-4360 |
| Keywords [eng] |
polydopamine (PDA) ; ZnO-PDA nanocomposite ; photo-electrochemical glucose biosensor ; ITO modified glass electrode |
| Abstract [eng] |
Zinc oxide (ZnO) nanostructures are widely used in optical sensors and biosensors. Functionalization of these nanostructures with polymers enables optical properties of ZnO to be tailored. Polydopamine (PDA) is a highly biocompatible polymer, which can be used as a versatile coating suitable for application in sensor and biosensor design. In this research, we have grown ZnO-based nanorods on the surface of ITO-modified glass-plated optically transparent electrodes (glass/ITO). Then the deposition of the PDA polymer layer on the surface of ZnO nanorods was performed from an aqueous PDA solution in such a way glass/ITO/ZnO-PDA structure was formed. The ZnO-PDA composite was characterized by SEM, TEM, and FTIR spectroscopy. Then glucose oxidase (GOx) was immobilized using crosslinking by glutaraldehyde on the surface of the ZnO-PDA composite, and glass/ITO/ZnO-PDA/GOx-based biosensing structure was designed. This structure was applied for the photo-electrochemical determination of glucose (Glc) in aqueous solutions. Photo-electrochemical determination of glucose by cyclic voltammetry and amperometry has been performed by glass/ITO/ZnO-PDA/GOx-based biosensor. Here reported modification/functionalization of ZnO nanorods with PDA enhances the photo-electrochemical performance of ZnO nanorods, which is well suited for the design of photo-electrochemical sensors and biosensors. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2021 |
| CC license |
|
