Title Current treatment strategies for patients with only peritoneal cytology positive stage IV gastric cancer /
Authors Baušys, Augustinas ; Baušys, Rimantas ; Lukšta, Martynas ; Gricius, Žilvinas ; Aniukštytė, Laura ; Bičkaitė, Klaudija ; Strupas, Kęstutis
DOI 10.12998/wjcc.v9.i32.9711
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Is Part of World Journal of Clinical Cases.. Pleasanton, CA : Baishideng Publishing Group Inc.. 2021, vol. 9, iss. 32, p. 9711-9721.. ISSN 2307-8960. eISSN 2307-8960
Keywords [eng] gastrectomy ; gastric cancer ; intraperitoneal chemotherapy ; positive peritoneal cytology ; systemic chemotherapy
Abstract [eng] Gastric cancer (GC) is one of the most common malignancies worldwide and surgery remains the only potentially curative treatment option for it. Although a significant proportion of GC patients are found with distant metastases already at the initial diagnosis. Peritoneal dissemination is the most common site of metastases. Positive peritoneal cytology (Cy1) is associated with poor long-term outcomes; thus, these patients are considered as stage IV even if macroscopic carcinomatosis is absent. Currently, there is no clear evidence for the most optimal treatment for this distinct subpopulation of the stage IV cohort. Available strategies vary from palliative chemotherapy to upfront gastrectomy. This comprehensive review summarized current evidence of different treatment strategies for Cy1 GC including roles of surgery, systemic and intraperitoneal chemotherapy.
Published Pleasanton, CA : Baishideng Publishing Group Inc
Type Journal article
Language Lithuanian
Publication date 2021
CC license CC license description