Title Left atrial volume changes during exercise stress echocardiography in heart failure and hypertrophic cardiomyopathy: Exercise echocardiography and left atrial changes /
Authors Wierzbowska-Drabik, Karina ; Kasprzak, Jarosław D ; Haberka, Maciej ; Peteiro, Jesus ; Re, Federica ; D'Alfonso, Maria Grazia ; Mori, Fabio ; Palinkas, Eszter D ; Agoston, Gergely ; Varga, Albert ; Djordjevic-Dikic, Ana ; Tesic, Milorad ; Zagatina, Angela ; Rodriguez-Zanella, Hugo ; Simova, Iana ; Merli, Elisa ; Morrone, Doralisa ; D'Andrea, Antonello ; Camarozano, Ana C ; Reisenhofer, Barbara ; Prota, Costantina ; Citro, Rodolfo ; Čelutkienė, Jelena ; Boshchenko, Alla ; Ciampi, Quirino ; Picano, Eugenio
DOI 10.1016/j.hjc.2022.01.003
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Is Part of Hellenic journal of cardiology.. Athens : Hellenic Cardiological Society. 2022, vol. 67, p. 9-18.. ISSN 1109-9666. eISSN 2241-5955
Keywords [eng] E/e’ ratio ; exercise stress echocardiography ; left atrial volume index ; left ventricular ejection fraction ; mitral regurgitation
Abstract [eng] BACKGROUND: We assessed feasibility and functional correlates of LAVI (left atrial volume index) changes during exercise stress echocardiography (ESE). METHODS: ESE on bike or treadmill was performed in 363 patients with heart failure with preserved ejection fraction (HFpEF, n = 173), reduced ejection fraction (HFrEF, n = 59) or hypertrophic cardiomyopathy (HCM, n=131). LAVI stress-rest increase ≥ 6.8 ml/m2 was defined as dilation. RESULTS: LAVI measurements were feasible in 100%. LAVI did not change in HFrEF being at rest 32 (25-45) vs. at stress 36 (24 - 54) ml/m2, P = NS and in HCM at rest 35 (26 - 48) vs. at stress 38 (28 - 48) ml/m2, P = NS whereas it decreased in HFpEF from 30 (24 -40) to 29 (21 - 37) ml/m2 at stress, P = 0.007. LA dilation occurred in 107 (30%) patients (27% with treadmill vs. 33% with bike ESE, P = NS): 26 with HFpEF (15%), 26 with HFrEF (44%) and 55 with HCM (42%) with P 14 at rest with OR 4.4, LVEF < 50% with OR 2.9, and LAVI at rest < 35 ml/m2 with OR 2.7. CONCLUSION: LAVI assessment during ESE was highly feasible and dilation equally frequent with treadmill or bike. LA dilation was threefold more frequent in HCM and HFrEF and could be predicted by increased resting E/e' and impaired EF as well as smaller baseline LAVI.
Published Athens : Hellenic Cardiological Society
Type Journal article
Language English
Publication date 2022
CC license CC license description