| Title |
Increase of myocardial ischemia time and short-term prognosis of patients with acute myocardial infarction during the first COVID-19 pandemic wave / |
| Authors |
Budrys, Povilas ; Lizaitis, Mindaugas ; Čerlinskaitė-Bajorė, Kamilė ; Bajoras, Vilhelmas ; Rodevič, Greta ; Martinonytė, Aurelija ; Diečkus, Laurynas ; Badaras, Ignas ; Šerpytis, Pranas ; Gurevičius, Romualdas ; Višinskienė, Rasa ; Buivydas, Romualdas ; Volodko, Aleksandr ; Urbonaitė, Eglė ; Čelutkienė, Jelena ; Davidavičius, Giedrius |
| DOI |
10.3390/medicina57121296 |
| Full Text |
|
| Is Part of |
Medicina (Lithuania).. Basel : MDPI. 2021, vol. 57, iss. 12, art. no. 1296, p. [1-11].. ISSN 1010-660X. eISSN 1648-9144 |
| Keywords [eng] |
COVID-19 ; ischemia time ; myocardial infarction ; percutaneous coronary intervention |
| Abstract [eng] |
Background and objectives: early reports showed a decrease in admission rates and an increase in mortality of patients with acute myocardial infarction (AMI) during the first wave of COVID-19 pandemic. We sought to investigate whether the COVID-19 pandemic and associated lockdown had an impact on the ischemia time and prognosis of patients suffering from AMI in the settings of low COVID-19 burden. Materials and Methods: we conducted a retrospective data analysis from a tertiary center in Lithuania of 818 patients with AMI. Data were collected from 1 March to 30 June in 2020 during the peri-lockdown period (2020 group; n = 278) and compared to the same period last year (2019 group; n = 326). The primary study endpoint was all-cause mortality during 3 months of follow-up. Secondary endpoints were heart failure severity (Killip class) on admission and ischemia time in patients with acute ST segment elevation myocardial infarction (STEMI). Results: there was a reduction of 14.7% in admission rate for acute myocardial infarction (AMI) during the peri-lockdown period. The 3-month mortality rate did not differ significantly (6.9% in 2020 vs. 10.5% in 2019, p = 0.341 for STEMI patients; 5.3% in 2020 vs. 2.6% in 2019, p = 0.374 for patients with acute myocardial infarction without ST segment elevation (NSTEMI)). More STEMI patients presented with Killip IV class in 2019 (13.5% vs. 5.5%, p = 0.043, respectively). There was an increase of door-to-PCI time (54.0 [42.0-86.0] in 2019; 63.5 [48.3-97.5] in 2020, p = 0.018) and first medical contact (FMC)-to-PCI time (101.0 [82.5-120.8] in 2019; 115 [97.0-154.5] in 2020, p = 0.01) during the pandemic period. Conclusions: There was a 14.7% reduction of admissions for AMI during the first wave of COVID-19. FMC-to-PCI time increased during the peri-lockdown period, however, it did not translate into worse survival during follow-up. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2021 |
| CC license |
|
