Title Successful treatment of primary headache associated with sexual activity using erenumab: Case report /
Authors Makarevičius, Gytis ; Ryliškienė, Kristina
DOI 10.1177/03331024221075074
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Is Part of Cephalalgia.. London : SAGE Publications Ltd. 2022, vol. 42, iss. 7, p. 680-683.. ISSN 0333-1024. eISSN 1468-2982
Keywords [eng] Primary headache associated with sexual activity ; migraine ; calcitonin gene-related peptide ; erenumab ; case report
Abstract [eng] Background Primary headache associated with sexual activity is a rare benign headache disorder that is provoked by sexual excitement. It is a diagnosis of exclusion after the underlying secondary causes have been ruled out. The cause of this headache disorder is still unknown. Cerebral vasospasm, pericranial muscular contraction, hemodynamic and respiratory changes during sexual activity are most commonly listed as possible pathophysiological mechanisms. Several acute and prophylactic options with good clinical response have been described in the case series. Case report We present a case of a 30-year-old woman with primary headache associated with sexual activity and comorbid with frequent episodic migraine without aura. Both headache disorders were successfully managed with monoclonal antibody against calcitonine gene-related peptide (CGRP) receptor erenumab 70 mg. Conclusion The efficacy of erenumab in our case presumes that CGRP might also be an important mediator in facilitating primary headache associated with sexual activity.
Published London : SAGE Publications Ltd
Type Journal article
Language English
Publication date 2022
CC license CC license description