Title Pooperacinės imunomitybos poveikis ląsteliniam ir sisteminiam uždegiminiam atsakui bei išeitims mažos operacinės rizikos ligoniams po širdies operacijų /
Translation of Title Effects of postoperative immunonutrition on cellular and systemic immune responses and outcomes in low-risk cardiac surgery.
Authors Svetikienė, Marija
DOI 10.15388/vu.thesis.309
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Pages 152
Keywords [eng] cardiosurgery ; immunonutrition ; glutamine ; cellular immunity ; systemic immune response
Abstract [eng] Surgical treatment remains a very important and indispensable part of the complex treatment of cardiovascular diseases. Cardiac surgery with cardioplumonary bypass causes significant changes in homeostasis and a more or less strong immune response. Depending on its severity and the patient's physiological reserve, this may have a direct impact not only on postoperative morbidity and mortality, but, in turn, on the patient's quality of life and late survival. A closer look reveals that the incidence or incidence of complications after heart surgery remains high, up to 42%, depending on the type of surgery and the preoperative condition of the patient. All this can be explained by the fact that with the improvement of surgical techniques and the introduction of new methodologies, as well as the improvement of intensive care techniques, patients are being operated on older and more complex patients with reduced physiological reserves. In this study, we selected low-risk cardiac surgical patients with decreased cell viability and immunonutrition as a hypothesis, an opportunity, and possibly a way to stabilize the immune response and improve clinical outcomes after cardiac surgery, along with a one-year assessment.
Dissertation Institution Vilniaus universitetas.
Type Doctoral thesis
Language Lithuanian
Publication date 2022