| Title |
Organų sistemų funkcijų sutrikimo paplitimas, rizikos veiksniai, įtaka sergamumui ir mirštamumui kritinių būklių onkohematologinių ligonių populiacijoje / |
| Translation of Title |
Organ dysfunction in critically ill oncohaemathological patients: prevalence, risk factors, impact on mortality. |
| Authors |
Judickas, Šarūnas |
| DOI |
10.15388/vu.thesis.308 |
| Full Text |
|
| Pages |
154 |
| Keywords [eng] |
Oncohaematology ; intensive care ; mortality ; organ dysfunction |
| Abstract [eng] |
The incidence of new cancer cases is growing in Lithuania. Mortality of patients with blood cancer is high especially when condition of the patient is deteriorating and there is a need to transfer patient to intensive care unit (ICU). The aim of our study was to investigate the course of treatment in ICU of oncohaematological patients and to analyse the risk factors of mortality. There are no studies performed which analyse this population of the patients in Lithuania. Our results showed that organ dysfunctions on admission to ICU were mild and progressed to half of the patients over the first 48 hours in ICU. The largest part of patients required organ support. Mortality in ICU reached 44,47 % and it did not differ between the age groups. The mortality was higher in patients who had advanced organ dysfunctions based on SOFA score (≥ 10 points) on ICU admission also for those patients when SOFA score increased over the first 48 hours in ICU. We found that independent risk factors for mortality in the ICU are qSOFA ≥ 2, increasing SOFA score over the first 48 h in intensive care unit, need for invasive mechanical ventilation on the first day in the ICU, suspected or confirmed A. baumannii infection in intensive care unit, lower arterial pH on admission to intensive care unit. |
| Dissertation Institution |
Vilniaus universitetas. |
| Type |
Doctoral thesis |
| Language |
Lithuanian |
| Publication date |
2022 |
