| Title |
A survey on thromboprophylaxis and coagulation assessment in children and young adults with acute lymphoblastic leukaemia (ALL) in the Nordic and Baltic countries: different practices of assessment and management / |
| Authors |
Andersson, Nadine G ; Rathe, Mathias ; Mølle, Ingolf ; Jarvis, Kirsten Brunswig ; Hoffmann, Marianne ; Huurre, Anu ; Joelsson, Joel ; Albertsen, Birgitte Klug ; Lohi, Olli ; Långström, Satu ; Overgaard, Ulrik ; Šaulytė Trakymienė, Sonata ; Vepsäläinen, Kaisa ; Vogt, Hartmut ; Ranta, Susanna |
| DOI |
10.1111/bjh.18397 |
| Full Text |
|
| Is Part of |
British journal of haematology.. Hoboken : Wiley. 2022, vol. 199, iss. 1, p. 117-121.. ISSN 0007-1048. eISSN 1365-2141 |
| Keywords [eng] |
ALL ; antithrombin ; childhood leukaemia ; paediatric haemostasis ; paediatric thrombosis ; thrombosis |
| Abstract [eng] |
Patients undergoing treatment for acute lymphoblastic leukaemia (ALL) are at risk of coagulopathy, especially thromboembolism. We conducted a survey on practices in the assessment and management of coagulopathy during the new ALLTogether protocol in 29 (17 paediatric, 12 adult) Nordic and Baltic cancer centres. While 92% of adult centres used thromboprophylaxis with low-molecular-weight heparin, no paediatric centre did. Almost all providers performed baseline coagulation studies, but only 59% continued the assessment. Fibrinogen replacement was conducted in 59%, and antithrombin replacement in 28% of the centres. The survey highlights the need for guidelines in the management of coagulopathy during ALL therapy. |
| Published |
Hoboken : Wiley |
| Type |
Journal article |
| Language |
English |
| Publication date |
2022 |
| CC license |
|
