Expansion of the global RNA virome reveals diverse clades of bacteriophages /

Uri Neri; Yuri I Wolf; Simon Roux; Antonio Pedro Camargo; Benjamin Lee; Darius Kazlauskas; I. Min Chen; Natalia Ivanova; Lisa Zeigler Allen; David Paez-Espino; Donald A Bryant; Devaki Bhaya; Adrienne B Narrowe; Alexander J Probst; Alexander Sczyrba; Annegret Kohler; Armand Séguin; Ashley Shade; Barbara J Campbell; Björn D Lindahl; Brandi Kiel Reese; Breanna M Roque; Chris DeRito; Colin Averill; Daniel Cullen; David A.C Beck; David A Walsh; David M Ward; Dongying Wu; Emiley Eloe-Fadrosh; Eoin L Brodie; Erica B Young; Erik A Lilleskov; Federico J Castillo; Francis M Martin; Gary R LeCleir; Graeme T Attwood; Hinsby Cadillo-Quiroz; Holly M Simon; Ian Hewson; Igor V Grigoriev; James M Tiedje; Janet K Jansson; Janey Lee; Jean S VanderGheynst; Jeff Dangl; Jeff S Bowman; Jeffrey L Blanchard; Jennifer L Bowen; Jiangbing Xu; Jillian F Banfield; Jody W Deming; Joel E Kostka; John M Gladden; Josephine Z Rapp; Joshua Sharpe; Katherine D McMahon; Kathleen K Treseder; Kay D Bidle; Kelly C Wrighton; Kimberlee Thamatrakoln; Klaus Nusslein; Laura K Meredith; Lucia Ramirez; Marc Buee; Marcel Huntemann; Marina G Kalyuzhnaya; Mark P Waldrop; Matthew B Sullivan; Matthew O Schrenk; Matthias Hess; Michael A Vega; Michelle A O'Malley; Monica Medina; Naomi E Gilbert; Nathalie Delherbe; Olivia U Mason; Paul Dijkstra; Peter F Chuckran; Petr Baldrian; Philippe Constant; Ramunas Stepanauskas; Rebecca A Daly; Regina Lamendella; Robert J Gruninger; Robert M McKay; Samuel Hylander; Sarah L Lebeis; Sarah P Esser; Silvia G Acinas; Steven S Wilhelm; Steven W Singer; Susannah S Tringe; Tanja Woyke; T. B.K Reddy; Terrence H Bell; Thomas Mock; Tim McAllister; Vera Thiel; Vincent J Denef; Wen-Tso Liu; Willm Martens-Habbena; Xiao-Jun Allen Liu; Zachary S Cooper; Zhong Wang; Mart Krupovic; Valerian V Dolja; Nikos C Kyrpides; Eugene V Koonin; Uri Gophna

doi:10.1016/j.cell.2022.08.023

Title	Expansion of the global RNA virome reveals diverse clades of bacteriophages /
Authors	Neri, Uri ; Wolf, Yuri I ; Roux, Simon ; Camargo, Antonio Pedro ; Lee, Benjamin ; Kazlauskas, Darius ; Chen, I. Min ; Ivanova, Natalia ; Zeigler Allen, Lisa ; Paez-Espino, David ; Bryant, Donald A ; Bhaya, Devaki ; Narrowe, Adrienne B ; Probst, Alexander J ; Sczyrba, Alexander ; Kohler, Annegret ; Séguin, Armand ; Shade, Ashley ; Campbell, Barbara J ; Lindahl, Björn D ; Reese, Brandi Kiel ; Roque, Breanna M ; DeRito, Chris ; Averill, Colin ; Cullen, Daniel ; Beck, David A.C ; Walsh, David A ; Ward, David M ; Wu, Dongying ; Eloe-Fadrosh, Emiley ; Brodie, Eoin L ; Young, Erica B ; Lilleskov, Erik A ; Castillo, Federico J ; Martin, Francis M ; LeCleir, Gary R ; Attwood, Graeme T ; Cadillo-Quiroz, Hinsby ; Simon, Holly M ; Hewson, Ian ; Grigoriev, Igor V ; Tiedje, James M ; Jansson, Janet K ; Lee, Janey ; VanderGheynst, Jean S ; Dangl, Jeff ; Bowman, Jeff S ; Blanchard, Jeffrey L ; Bowen, Jennifer L ; Xu, Jiangbing ; Banfield, Jillian F ; Deming, Jody W ; Kostka, Joel E ; Gladden, John M ; Rapp, Josephine Z ; Sharpe, Joshua ; McMahon, Katherine D ; Treseder, Kathleen K ; Bidle, Kay D ; Wrighton, Kelly C ; Thamatrakoln, Kimberlee ; Nusslein, Klaus ; Meredith, Laura K ; Ramirez, Lucia ; Buee, Marc ; Huntemann, Marcel ; Kalyuzhnaya, Marina G ; Waldrop, Mark P ; Sullivan, Matthew B ; Schrenk, Matthew O ; Hess, Matthias ; Vega, Michael A ; O'Malley, Michelle A ; Medina, Monica ; Gilbert, Naomi E ; Delherbe, Nathalie ; Mason, Olivia U ; Dijkstra, Paul ; Chuckran, Peter F ; Baldrian, Petr ; Constant, Philippe ; Stepanauskas, Ramunas ; Daly, Rebecca A ; Lamendella, Regina ; Gruninger, Robert J ; McKay, Robert M ; Hylander, Samuel ; Lebeis, Sarah L ; Esser, Sarah P ; Acinas, Silvia G ; Wilhelm, Steven S ; Singer, Steven W ; Tringe, Susannah S ; Woyke, Tanja ; Reddy, T. B.K ; Bell, Terrence H ; Mock, Thomas ; McAllister, Tim ; Thiel, Vera ; Denef, Vincent J ; Liu, Wen-Tso ; Martens-Habbena, Willm ; Allen Liu, Xiao-Jun ; Cooper, Zachary S ; Wang, Zhong ; Krupovic, Mart ; Dolja, Valerian V ; Kyrpides, Nikos C ; Koonin, Eugene V ; Gophna, Uri
DOI	10.1016/j.cell.2022.08.023
Full Text
Is Part of	Cell.. Cambridge, MA : Cell Press. 2022, vol. 185, iss. 21, p. 4023-4037, e1-e18.. ISSN 0092-8674. eISSN 1097-4172
Keywords [eng]	Bactriophage ; Functional protein annotation ; Metatranscriptomics ; RNA dependent RNA polymerase ; RNA Virus ; Viral Ecology ; viral phylogeny ; Virus ; Virus - Host prediction
Abstract [eng]	High-throughput RNA sequencing offers broad opportunities to explore the Earth RNA virome. Mining 5,150 diverse metatranscriptomes uncovered >2.5 million RNA virus contigs. Analysis of >330,000 RNA-dependent RNA polymerases (RdRPs) shows that this expansion corresponds to a 5-fold increase of the known RNA virus diversity. Gene content analysis revealed multiple protein domains previously not found in RNA viruses and implicated in virus-host interactions. Extended RdRP phylogeny supports the monophyly of the five established phyla and reveals two putative additional bacteriophage phyla and numerous putative additional classes and orders. The dramatically expanded phylum Lenarviricota, consisting of bacterial and related eukaryotic viruses, now accounts for a third of the RNA virome. Identification of CRISPR spacer matches and bacteriolytic proteins suggests that subsets of picobirnaviruses and partitiviruses, previously associated with eukaryotes, infect prokaryotic hosts.
Published	Cambridge, MA : Cell Press
Type	Journal article
Language	English
Publication date	2022
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„Expansion of the global RNA virome reveals diverse clades of bacteriophages /“