Title Fetal tibial artery doppler in late IUGR fetuses: a longitudinal study /
Authors Norvilaitė, Kristina ; Ramašauskaitė, Diana ; Bartkevičienė, Daiva ; Šliachtenko, Aleksandra ; Kurmanavičius, Juozas
DOI 10.3390/jcm12010082
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Is Part of Journal of clinical medicine.. Basel : MDPI. 2023, vol. 12, iss. 1, art. no. 82, p. [1-9].. ISSN 2077-0383. eISSN 2077-0383
Keywords [eng] ate-onset IUGR ; CPR ; doppler examination ; fetal tibial artery ; pregnancy ; intrauterine hypoxia
Abstract [eng] Introduction: Late-onset intrauterine fetal growth restriction (IUGR) is a common pregnancy complication diagnosed in 5–10% of pregnant women worldwide. Under the impact of hypoxia, the fetus develops a protective mechanism of adaptive changes occurring in the cerebral circulation (“brain-sparing effect”). Materials and methods: We conducted detailed longitudinal Doppler examinations and the monitoring of the fetal condition in 53 IUGR fetuses. Doppler measurements of the pulsatility index in the fetal tibial (TA-PI), umbilical (UA-PI), and middle cerebral arteries (MCA-PI) were performed, and the cerebral placental ratio (CPR) was determined on a weekly basis from the 33rd week to the birth. Results: The longitudinal analysis showed a significant increase in the TA-PI. The UA showed a plateau, but no increase was detected near term. The MCA-PI and CPR showed a progressive decrease in values from inclusion to delivery. Our findings indicate that the increase in the TA-PI was the first sign of the aggravating state of the fetus with the changes registered from the 35th week. The parameters of the UA-PI did not show significant changes, while the MCA and CPR became abnormal later from the 37th week. Conclusions: These observations can serve towards the development of guidelines for detecting the deteriorating signs and intervention timing in IUGR during late pregnancies.
Published Basel : MDPI
Type Journal article
Language English
Publication date 2023
CC license CC license description