Title Exclusion of Disperse Orange 3 is possible from the textile dye mix present in the Swedish baseline patch test series. A study by the Swedish Contact Dermatitis Research Group /
Authors Isaksson, Marléne ; Antelmi, Annarita ; Dahlin, Jakob ; Stenton, Joanna ; Svedman, Cecilia ; Zimerson, Erik ; Glas, Bo ; Hagvall, Lina ; Lagrelius, Maria ; Löwnertz, Anna ; Malinauskienė, Laura ; Matura, Mihaly ; Bruze, Magnus
DOI 10.1111/cod.14223
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Is Part of Contact dermatitis.. Hoboken : Wiley-Blackwell Publishing Ltd.. 2023, vol. 88, iss. 1, p. 54-59.. ISSN 0105-1873. eISSN 1600-0536
Keywords [eng] allergic contact dermatitis ; contact allergy ; delayed hypersensitivity ; disperse dyes ; patch testing ; textile dermatitis
Abstract [eng] Background: The textile dye mix (TDM) 6.6% in petrolatum contains Disperse Blue (DB) 35, Disperse Yellow 3, Disperse Orange (DO) 1 and 3, Disperse Red 1 and 17, and DB 106 and 124. The most frequent allergen in TDM-positive patients is DO 3. Around 85% of para-phenylenediamine (PPD)-allergic dermatitis patients have been positive to DO 3. There has been a discussion to exclude DO 3 from TDM 6.6% because of strong simultaneous reactions to TDM and PPD. Objectives: To study if DO 3 can be excluded from TDM 6.6%. Methods: Patch tests were performed on 1481 dermatitis patients with TDM 6.6%, TDM 7.0% (without DO 3 but the other disperse dyes at 1.0% each), DO 3 1.0%, and PPD 1.0% pet. Results: Contact allergy to TDM 6.6% was 3.6% and to TDM 7.0% was 3.0%. All 26 DO 3-positive patients were positive to PPD. The 44 patients positive to TDM 7.0% plus the 13 positive to PPD and TDM 6.6% but negative to TDM 7.0% were 57, outnumbering the 53 positive to TDM 6.6%. Conclusion: TDM 7.0% can replace TDM 6.6% in the Swedish baseline series, since TDM 7.0% together with PPD 1.0% will detect patients with textile dye allergy.
Published Hoboken : Wiley-Blackwell Publishing Ltd
Type Journal article
Language English
Publication date 2023
CC license CC license description