| Title |
Treatment methods of prostate cancer recurrence after radiotherapy. Current treatment alternatives and our clinical experience / |
| Another Title |
Prostatos vėžio recidyvų po spindulinės terapijos gydymo metodai Šiuolaikinėje medicinoje naudojami metodai ir mūsų klinikinė patirtis. |
| Authors |
Ulys, Albertas ; Vėželis, Alvydas ; Ivanauskas, Andrius ; Snicorius, Marius |
| DOI |
10.15388/LietChirur.2013.3.1840 |
| Full Text |
|
| Is Part of |
Lietuvos chirurgija.. Vilniaus universiteto leidykla. 2013, t. 12, Nr. 3, p. 138-143.. ISSN 1392-0995. eISSN 1648-9942 |
| Keywords [eng] |
prostate cancer ; cancer recurrence ; salvage treatment |
| Abstract [eng] |
Background / objective. Prostate cancer is the most common cancer among men of Lithuania. Every year about 3000 new cases of prostate cancer are diagnosed in our country. Many patients receive radiotherapy as primary treatment. Unfortunately, after several years some of the patients are diagnosed with prostate cancer recurrence. These cases are more challenging and require to apply salvage treatment methods. The aim of this article is to present our clinical experience and discuss the main features, advantages and disadvantages of the treatment methods. Patients and methods. Retrospective analysis of 10 salvage prostate cancer recurrence treatment cases was completed. All patients previously received radiotherapy as primary treatment. 5 patients received salvage high-dose brachiterapy (group 1) and other 5-salvage cryotherapy (group 2). Prostate cancer recurrences were diagnosed by multiparametric MRI and ultrasound guided transrectal or transperineal biopsies. Results. Average patient age was 64,2±7,9 years in group 1 and 68±3,1 years in group 2. None of the patients had prostate cancer progression to lymph nodes (N) or metastases (M) on initial diagnosis or before salvage treatment. No intraoperative complications were observed. Average time between radiotherapy and salvage therapy in both groups was 88,9±30,1 months. In both groups 1 patient suffered from salvage treatment failure-prostate cancer progression was observed. Conclusions. Currently there is no perfect treatment method for recurrent prostate cancer. Every situation requires universal aproach. Our initial experience shows that salvage cryotherapy and brachiterapy can be a viable alternative for patients with disease progression after radiotherapy. |
| Published |
Vilniaus universiteto leidykla |
| Type |
Journal article |
| Language |
English |
| Publication date |
2013 |
| CC license |
|
