Title FFR guided PCI on long coronary lesions: 2-year clinical results with 2nd or newer generation DES /
Translation of Title Ilgų vainikinių arterijų susiaurėjimų PKI vadovaujantis frakcijinio tėkmės rezervo tyrimu: dvejų metų klinikiniai rezultatai naudojant antros ir naujesnės kartos vaistais dengtus stentus.
Authors Baranauskas, Arvydas ; Bajoras, Vilhelmas ; Budrys, Povilas ; Laucevičius, Aleksandras ; Davidavičius, Giedrius
DOI 10.6001/actamedica.v23i1.3264
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Is Part of Acta medica Lituanica.. Vilnius : Lietuvos mokslų akademija. 2016, vol. 23, no. 1, p. 5-10.. ISSN 1392-0138. eISSN 2029-4174
Keywords [eng] long coronary lesions ; FFR guided PCI ; drug-eluting stent
Abstract [eng] Background. Despite improvements in drug-eluting stent (DES) technology, treatment strategies for long coronary artery lesions remain a controversial issue. The aim of our study was to evaluate the long-term clinical results after FFR guided PCI on long coronary lesions. Materials and methods. A total of 74 consecutive patients with significant (mean FFR 0.61 ± 0.11) coronary artery lesions ≥30 mm in length were included in the prospective study. All patients were treated with FFR guided PCI implanting newer generation Biolimus, Everolimus or Zotarolimus eluting stents. Clinical endpoints – target vessel revascularization (TVR) and major adverse cardiac events (MACE) – were recorded at 1 and 2 years. Results. 100% angiographic procedure success was achieved, the mean post procedural FFR was 0.88 ± 0.06. At 2-year follow-up, 6 (8.1%) patients had ischemia driven TVR, all within the first 12 months. There were no target vessel related acute coronary syndromes and definite stent thromboses in the study group. At 2 years, the total MACE rate was 29.7%. There was a trend towards a higher TVR rate in patients with overlapping DES vs single DES implanted (9.6 vs 4.5%, p = 0.6). On regression analysis, the total stent length had no influence on the TVR rate. Conclusions. At 2 years after stenting long coronary lesions with newer generation DES the TVR rate was 8.1%, which is acceptable in the high cardiovascular risk population with diffuse coronary artery disease. The total stent length did not affect the long-term clinical outcomes.
Published Vilnius : Lietuvos mokslų akademija
Type Journal article
Language English
Publication date 2016
CC license CC license description