| Title |
Fluorescence-Lifetime Imaging Microscopy for Visualization of Quantum Dots’ Endocytic Pathway / |
| Authors |
Damalakienė, Leona ; Karabanovas, Vitalijus ; Bagdonas, Saulius ; Rotomskis, Ričardas |
| DOI |
10.3390/ijms17040473 |
| Full Text |
|
| Is Part of |
International journal of molecular sciences.. Basel : MDPI. 2016, Vol. 17, iss. 4, p. 1-8.. ISSN 1422-0067 |
| Keywords [eng] |
Quantum dots ; Fluorescence-lifetime imaging ; Endocytosis ; Intracellular distribution |
| Abstract [eng] |
Accumulation of carboxylated polyethylene glycol (PEG) CdSe/ZnSquantum dots (QDs) has been monitored in living fibroblasts using confocal microscopy for fluorescence intensity and fluorescence-lifetime imaging (FLIM). The wide range of mean photoluminescence (PL) lifetime values was observed for the intracellular QDs in different intracellular microenvironment, which revealed structural heterogeneity of endosomes and enabled the distinguishing among endosomes of different maturity. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2016 |
