Title Ambulatory and successive home-based heart rate targeted aerobic training improves arterial parameters: a follow-up study in people with metabolic syndrome /
Authors Zupkauskienė, Jūratė ; Laucevičienė, Ieva ; Ryliškytė, Ligita ; Navickas, Petras ; Kizlaitis, Romualdas Jonas ; Laucevičius, Aleksandras
DOI 10.1080/07853890.2023.2250363
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Is Part of Annals of medicine.. Abingdon : Taylor & Francis Ltd.. 2023, vol. 55, no. 2, art. no. 2250363, p. 1-13.. ISSN 0785-3890. eISSN 1365-2060
Keywords [eng] arterial stiffness ; carotid artery intima-media thickness ; metabolic syndrome ; physical activity ; outpatient aerobic training ; home-based training ; remote supervision ; wearable devices ; ecG heart rate monitoring
Abstract [eng] Background: studies demonstrated that outpatient aerobic exercise programs (aeP) can significantly decrease aortic stiffness in people with metabolic syndrome (Mets). there is some limited data that remotely supervised home-based aeP can also improve arterial stiffness in this population. We aimed to evaluate the changes in the arterial wall parameters after the 2-month ambulatory supervised aeP followed by the 6-month home-based aeP with and without targeting of heart rate (hR) by electrocardiogram (ecG) in people with Mets.Methods: in this prospective study (clinicaltrials.gov identifier: Nct05592704) 132 Mets subjects (mean age 52.44 ± 6.26 years, 54.55% female) were evaluated. at first, all subjects participated in the 2-month ambulatory supervised aeP, which consisted of 40 individual aerobic training sessions on a cycle ergometer 5 times/week for 40 min and received the recommendations for home-based training. then the study (n = 66) and the control (n = 66) groups participated in the 6-month home-based aeP, but only the study group subjects targeted their hR using ecG monitor connected to the smartphone during workouts. arterial stiffness parameters and carotid artery intima-media thickness (ciMt) were evaluated in all participants at baseline and after 8 months.Results: after 8 months, carotid-femoral pulse wave velocity (c-f PWV) significantly reduced in both groups (−12.22% in the study group vs. −7.85% in the control group, all p < .001) without a significant between-group difference (p = 0.144). a significant improvement of carotid-radial pulse wave velocity (c-r PWV) was observed only in the study group (-11.37%, p < .001, d = −0.671) with significant between-group difference (p < .001). the reduction of c-r PWV after 8 months of aeP occurred when c-r PWV at baseline was in the 2nd quartile (>7.90 m/s). a significant decrease of 3.32% in ciMt was present only in the study group (p = .032, d = −0.288).Conclusions: the combination of 2-month ambulatory supervised aeP and successive 6-month home-based aeP targeted by hR monitoring using ecG improved arterial properties in Metssubjects more than the same combination without hR targeting, leading to the greater reduction of c-r PWV and ciMt.
Published Abingdon : Taylor & Francis Ltd
Type Journal article
Language English
Publication date 2023
CC license CC license description