| Title | Vaccination practices in pediatric transplantation: A survey among member centers of the European reference network TransplantChild / |
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| Authors | Donà, Daniele ; Bravo-Gallego, Luz Yadira ; Remacha, Esteban Frauca ; Cananzi, Mara ; Gastaldi, Andrea ; Canizalez, Juan Torres ; Stephenne, Xavier ; Lacaille, Florence ; Lindemans, Caroline ; Calore, Elisabetta ; Galea, Nathalie ; Benetti, Elisa ; Nachbaur, Edith ; Sandes, Ana Rita ; Teixeira, Ana ; Ferreira, Sandra ; Klaudel-Dreszler, Maja ; Ackermann, Oanez ; Boyer, Olivia ; Espinosa, Laura ; Guereta, Luis García ; Sciveres, Marco ; Fischler, Björn ; Schwerk, Nicolaus ; Neland, Mette ; Nicastro, Emanuele ; Dello Strologo, Luca ; Toporski, Jacek ; Vainumae, Inga ; Rascon, Jelena ; Urbonas, Vaidotas ; del Rosal, Teresa ; López-Granados, Eduardo ; Perilongo, Giorgio ; Baker, Alastair ; Vega, Paloma Jara |
| DOI | 10.1111/petr.14589 |
| Full Text |
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| Is Part of | Pediatric transplantation.. Hoboken : John Wiley and Sons Inc. 2023, vol. 27, iss. 7, art. no. e14589, p. [1-9].. ISSN 1397-3142. eISSN 1399-3046 |
| Keywords [eng] | children ; immunosuppression ; transplant ; vaccination ; vaccine-preventable infections |
| Abstract [eng] | Background: There is considerable variation in vaccination practices between pediatric transplant centers. This study aims to evaluate active immunization attitudes and practices among ERN-TransplantChild centers and identify potential areas of improvement that could be addressed by shared evidence-based protocols. Methods: A cross-sectional questionnaire of attitudes and practices toward immunization of pediatric SOT and HSCT candidates and recipients was sent to a representative member of multidisciplinary teams from 27 European centers belonging to the ERN-TransplantChild. Results: A total of 28/62 SOT programs and 6/12 HSCT programs across 21 European centers participated. A quarter of centers did not have an on-site protocol for the immunizations. At the time of transplantation, pediatric candidates were fully immunized (80%–100%) in 57% and 33% of the SOT and HSCT programs. Variations in the time between vaccine administration and admission to the waiting list were reported between the centers, with 2 weeks for inactivated vaccines and variable time (2–4 weeks) for live-attenuated vaccines (LAVs). Almost all sites recommended immunization in the post-transplant period, with a time window of 4–8 months for the inactivated vaccines and 16–24 months for MMR and Varicella vaccines. Only five sites administer LAVs after transplantation, with seroconversion evaluated in 80% of cases. Conclusions: The immunization coverage of European pediatric transplant recipients is still inconsistent and far from adequate. This survey is a starting point for developing shared evidence-based immunization protocols for safe vaccination among pediatric transplant centers and generating new research studies. |
| Published | Hoboken : John Wiley and Sons Inc |
| Type | Journal article |
| Language | English |
| Publication date | 2023 |
| CC license |
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