| Title |
Successful treatment of stiff-person syndrome with plasmapheresis: case report and literature review / |
| Translation of Title |
Sėkmingas sustingusio žmogaus sindromo gydymas plazmafereze: atvejo pristatymas ir literatūros apžvalga. |
| Authors |
Nasvytis, Matas ; Kaladytė Lokominienė, Rūta |
| DOI |
10.29014/NS.2022.26.22 |
| Full Text |
|
| Is Part of |
Neurologijos seminarai.. Vilnius : Vilniaus universiteto leidykla. 2022, t. 26, Nr. 3(93), p. 155-160.. ISSN 1392-3064. eISSN 2424-5917 |
| Keywords [eng] |
stiff-person syndrome ; antibodies against glutamic acid decarboxylase ; plasmapheresis |
| Abstract [eng] |
Stiff-person syndrome (SPS) is a rare neurologic disease, most often caused by autoimmune process during which antibodies against glutamic acid decarboxylase (anti-GAD65) are synthesised. The main clinical symptoms, among which are axial and proximal leg muscle stiffness and painful spasms, are often provoked by external triggers. In addition to those, the disease presents with anxiety, phobias, and other psychiatric symptoms. The most notable SPS comorbidities include temporal lobe epilepsy and type 1 diabetes mellitus. In this article, we present a clinical case of a patient illustrating the course of the disease, diagnostic difficulties, and treatment options, all of which are discussed in the literature review. |
| Published |
Vilnius : Vilniaus universiteto leidykla |
| Type |
Journal article |
| Language |
English |
| Publication date |
2022 |
| CC license |
|
