Title Cytogenetic effects of low ionising radiation doses and biological dosimetry /
Translation of Title Mažų jonizuojančiosios spinduliuotės apšvitos dozių poveikio citogenetiniai tyrimai ir biologinė dozimetrija.
Authors Gricienė, Birutė
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Pages 35
Keywords [eng] ionising radiation ; radiation worker ; cytogenetic effects ; chromosome aberrations ; biological dosimetry
Abstract [eng] The intensive use of ionising radiation (IR) sources and development of IR technology is related to increased exposure and adverse health risk to workers and public. The unstable chromosome aberration analysis in the group of nuclear energy workers (N=84) has shown that doses below annual dose limit (50 mSv) can induce chromosome aberrations in human peripheral blood lymphocytes. Significantly higher frequencies of the total chromosome aberrations were determened in the study group when compared to the controls ((N=82). The risks were found to differ with the type of activities and occupational exposure. Activities related to internal and neutron exposure risk may be regarded as potentially more dangerous when compared to other activities related with external gamma exposure doses only. The impact of age and smoking to chromosome aberration frequency was found to be insignificant. The results of this study show that cytogenetic monitoring can be used for IR occupational exposure risk assessment for different occupational groups of radiation workers and may provide additional information to ensure and optimise the radiation protection of radiation workers. The gamma radiation (60Co) dose-response curves for chromosome aberrations in vitro were established in Lithuania for the first time. Application of the established dose-response curves enables to perform the biological dosimetry in the country, to assess the doses of the first responders and people accidentally exposed to IR. These curves can be used to specify the measured increased IR exposure dose for radiation workers, to confirm or reject the IR doses measured above the annual dose limit.
Type Summaries of doctoral thesis
Language English
Publication date 2010