| Title |
Amperometric biosensing of L-glutamate using reduced graphene oxide and glutamate oxidase / |
| Authors |
Šakinytė-Urbikienė, Ieva ; Gurevičienė, Vidutė ; Razumienė, Julija |
| Full Text |
|
| Is Part of |
Proceedings: Eurosensors XXXIV, Lecce, Italy, 10-13 September 2023.. Basel : MDPI. 2023, p. [1-2].. ISSN 2504-3900 |
| Keywords [eng] |
amperometric biosensor ; L-glutamate ; RGO ; Glutamate oxidase ; oxidation of ammonia |
| Abstract [eng] |
Determination of L-glutamate in biological media is very important since it is the most common excitatory neurotransmitter related to some neurological diseases such as Parkinson’s, communication dysfunction, stroke, epilepsy or schizophrenia. Aiming to study pathways of these diseases as well as for evaluation of medical treatment, it is very important to have rapid and reliable methods for the determination of L-glutamate. This study presents a new approach of enzymebased biosensor operating at -0.1V, what ensures its good sensitivity and selectivity. Reduced graphene oxide applied in the biosensor, allowed monitoring of L-glutamate via electro oxidation of NH3 released during the reaction catalyzed by Glutamate oxidase. |
| Published |
Basel : MDPI |
| Type |
Conference paper |
| Language |
English |
| Publication date |
2023 |
| CC license |
|
