| Title |
Reagentless glucose biosensor based on combination of platinum nanostructures and polypyrrole layer / |
| Authors |
German, Natalija ; Popov, Anton ; Ramanavičienė, Almira |
| DOI |
10.3390/bios14030134 |
| Full Text |
|
| Is Part of |
Biosensors.. Basel : MDPI AG. 2024, vol. 14, iss. 3, art. no. 134, p. [1-13].. eISSN 2079-6374 |
| Keywords [eng] |
glucose ; glucose oxidase ; 1,10-phenathroline-5,6-dione ; platinum nanostructures ; polypyrrole |
| Abstract [eng] |
Two types of low-cost reagentless electrochemical glucose biosensors based on graphite rod (GR) electrodes were developed. The electrodes modified with electrochemically synthesized platinum nanostructures (PtNS), 1,10-phenanthroline-5,6-dione (PD), glucose oxidase (GOx) without and with a polypyrrole (Ppy) layer—(i) GR/PtNS/PD/GOx and (ii) GR/PtNS/PD/GOx/Ppy, respectively, were prepared and tested. Glucose biosensors based on GR/PtNS/PD/GOx and GR/PtNS/PD/GOx/Ppy electrodes were characterized by the sensitivity of 10.1 and 5.31 μA/(mM cm2), linear range (LR) up to 16.5 and 39.0 mM, limit of detection (LOD) of 0.198 and 0.561 mM, good reproducibility, and storage stability. The developed glucose biosensors based on GR/PtNS/PD/GOx/Ppy electrodes showed exceptional resistance to interfering compounds and proved to be highly efficient for the determination of glucose levels in blood serum. |
| Published |
Basel : MDPI AG |
| Type |
Journal article |
| Language |
English |
| Publication date |
2024 |
| CC license |
|
