| Abstract [eng] |
Master’s thesis by Viktorija Aičaitė, supervisor – dr. Kostas Ivanauskas. Vilnius University, Faculty of Medicine, Institute of Biomedical Sciences (Pharmacy and pharmacology center). Title of thesis: Nonsteroidal anti-inflammatory drug for alcohol hangover relief Aim: To evaluate the use of nonsteroidal anti-inflammatory drug use to treat alcohol hangover symptoms in Lithuania. Objectives: 1. To determine how often Lithuanians suffer from alcohol hangover; 2. Identify the most common and severe symptoms caused due to alcohol hangover; 3. To establish an understanding about the knowledge and frequency of nonsteroidal anti-inflammatory drug use by Lithuanians who use such drugs for alcohol hangover relief; 4. Determine what nonsteroidal anti-inflammatory drugs people use the most for alcohol hangover relief. Methodology: Quantitative research, online questionnaire was used to gather data. 1. Research subject- alcohol hangover symptoms and their severity, people who suffer from alcohol hangovers knowledge about NSAIDs, analgesics their use and how frequent they’re being used. 2. Research participants – 20year-olds and older Lithuanians. Research time period – 2022 November, until 2023 February. In total data gathered from 363 participants (feedback 95.8%), from all candidates that fits the criteria and answered all questions in total were 241 respondents. Data analysis was completed using R Commander x64 version 4.2.2. Results of research: During the research was found that 97% of respondents consume alcohol and the majority (30%, n=110) consume alcohol every week, also during a single alcohol consumption period majority of participants (30%, n=105) consume 3 to 4 ABV. It was determined, that 91% (n=330) of candidates have experienced alcohol hangovers and 28% (n=91) of respondents experience it every time they consume alcohol. By analysing the findings, established that the most frequent and severe symptom caused by the alcohol hangover – headache. Additional findings, people who don’t know what is NSAIDs 24% (n=80) participants, those who know but lacks knowledge 44% (n=144). Many respondents (73%) choose to treat alcohol hangover with NSAIDs and the main choice drug – ibuprofen (47%, n=113), main drug form for consumption – pill (76%, n=182). Selected drug is usually preferred for treating – headaches (98%, n=235) and 54% of participants selected that their choice of drug helps them treat the symptom every time. 64% of respondents stated that they haven’t experienced any drug side effects during alcohol hangover and 33% of participants noted that they don’t know what drug side effects are there. And most respondents (76%, n=182) choose to not consult with the pharmacist when buying NSAIDs. Conclusions: 1. During the research it was found that most participants do suffer from alcohol hangover and that the significant number of participants who experience alcohol hangover experience symptoms regarding alcohol hangover. 2. Data analysis of alcohol hangover caused symptoms revealed that the most severe symptoms are: headache, increased thirst, sleepiness, and nausea. 3. Research findings revealed that most respondents who suffer from alcohol hangover symptoms don’t know what NSAIDs is and what are they being used for, or they lack information about it. Also, during the research, it was found that most of the participants chooses to take NSAIDs every second time they experience alcohol hangover. And every time NSAIDs is being used to relieve symptoms cause by alcohol hangover is by most men. 4. During the research it was found out that the most common drug of choice is ibuprofen, paracetamol, and acetylsalicylic acid. The most common state the drugs are being used – pills. |
