Title |
Infectious epilepsies. literature review / |
Translation of Title |
Infectious Epilepsies. Literature Review. |
Authors |
Goth, Alessia |
Full Text |
|
Pages |
20 |
Keywords [eng] |
Infectious Epilepsy, Acute Symptomatic Seizures, CNS-Infection, Encephalitis, Meningitis, Neurocysticercosis, Epileptogenesis |
Abstract [eng] |
Infectious epilepsy can be diagnosed in patients with unprovoked seizures for which the cause is a previous limited and already healed infectious disease, suspected to have evoked changes in the brain tissue making it more susceptible to producing abnormal and excessive electrical discharges. Patients who underwent an infection have been recognized to have a higher risk of later developing epilepsy. Even as today many associated pathogens are known, the mechanisms of epileptogenesis and seizure production are still mostly undiscovered. Although we have some studies highlighting the differences of pathomechanism form other epilepsy etiologies, a lot more research hast to be done, especially regarding finding specific treatment aimed towards stopping the reorganizational changes of brain tissue after infection. Those treatments could help millions of people worldwide and decrease the burden of disease of epilepsy significantly. And while the treatment of infectious epilepsy doesn’t necessarily differ from other etiologies of epilepsy, it is important to recognize the underlying etiology of acute symptomatic seizures to initiate correct treatment and reduce overall mortality and morbidity. The goal of this narrative literature review is to give an overview of acute symptomatic seizures due to infections, the subsequent development of infectious epilepsy, current understanding of epileptogenesis, and helping understand the differentiation of seizures from epilepsy for right diagnosis and treatment. |
Dissertation Institution |
Vilniaus universitetas. |
Type |
Master thesis |
Language |
English |
Publication date |
2023 |