| Abstract [eng] |
Introduction: As minimally invasive methods such as core needle biopsy are getting more and more popular in diagnosing hematological malignancies, the preference for excisional biopsy is getting reconsidered. That is why the main objective of this retrospective study was to evaluate the diagnostic accuracy of core needle biopsy in diagnosing hematological malignancies and to find out if this method is suitable to replace standard excisional biopsy. Research participants and methods: A retrospective study included 313 lymph node biopsies of different locations performed under ultrasound control on hematological patients in 2017-2020 in Vilnius University Hospital Santaros Klinikos. Biopsies were divided in two groups (false and correct diagnostic value) by the received histological results. Diagnostic accuracy of core needle biopsy was calculated by the percentage of correct diagnostic value biopsies in all performed biopsies. The number and total length of cores, needle size and hematological diagnosis (Hodgkin’s or non-Hodgkin’s lymphoma) were also compared in these groups. Data were statistically significant when p < 0,05. Results: Excellent diagnostic accuracy of core needle biopsy was obtained in 97.8 % of cases and was completely sufficient for the diagnosis of hematological malignancies. A statistically significant difference was found between the diagnostic value groups in total core length (p = 0.013), needle size (p = 0.019) and hematological diagnosis (p = 0.039). The number of cores was not statistically significant in these groups (p = 0,886). Conclusion: The excellent diagnostic accuracy of core needle biopsy obtained in this study – 97.8 % and similar results of diagnostic accuracy demonstrated in literature indicate that core needle biopsy under the ultrasound guidance may replace excisional biopsy as a first line diagnostic measure for hematological malignancies in the near future if sufficient amount of biopsy material is collected, which could be done by using larger diameter needles and taking multiple cores. |
