| Abstract [eng] |
Gastric adenocarcinoma and hepatocellular carcinoma have relatively high morbidity and mortality but together these tumors are uncommon, especially synchronous. Tumors considered to be synchronous when diagnosed in less than 6 months apart, have different histology, possibility of one being metastases of another are ruled out, and malignancy of both tumors is proved. Male patients of older age, with alcohol consumption or tobacco smoking in their anamnesis who are obese or overweight and has or had hepatitis C infection are at increased risk of developing both gastric adenocarcinoma and hepatocellular carcinoma. Unlike hepatocellular carcinoma, treatment for hepatitis C, especially with direct-acting antiviral agents, does not reduce the risk of developing gastric adenocarcinoma. According to various sources, in the presence of synchronous gastrointestinal tumors, more radical treatment such as partial liver resection or liver transplantation should be considered, as patient survival is more dependent on relapse of hepatocellular carcinoma than on gastric adenocarcinoma and its complications. Once hepatitis C has been diagnosed, regular preventive check-ups are important to diagnose tumors as early as possible and appropriate multidisciplinary treatment should be instituted in a timely manner. This study describes a 62-year-old patient who was accidentally diagnosed with recurrent chronic hepatitis C at the age of 48 years and was diagnosed with synchronous hepatocellular carcinoma with gastric adenocarcinoma after 14 years during which the patient had almost no screening for liver damage. As this phenomenon is exceptionally rare, it is important to examine these cases, considering improving medical options, the increasing survival of patients with hepatitis, gastric and / or liver cancer. |
