Title Tinklainės arterijos makroaneurizmos diagnostika ir gydymas /
Translation of Title Diagnosis and management of retinal arterial macroaneurysm.
Authors Lagunavičiūtė, Tėja
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Pages 25
Abstract [eng] Objective: To conduct a literature review and to summarize the diagnosis and treatment of retinal arterial macroaneurysm discussed in the latest scientific publications. Methods: The literature search was performed using the database PubMed. In this literature review full text articles were analysed, which were: published in 2017 – 2022; written in the English language; relevant to the objective of the work. Objective: To conduct a literature review and to summarize the diagnosis and treatment of retinal arterial macroaneurysm discussed in the latest scientific publications. Methods: The literature search was performed using the database PubMed. In this literature review full text articles were analysed, which were: published in 2017 – 2022; written in the English language; relevant to the objective of the work. Results: After conducting a literature search and selection, 10 publications were included in this literature review. In all analysed studies retinal arterial macroaneurysm was diagnosed by examinations of eye fundus, fluorescein angiography or indocyanine green angiography and optical coherence tomography. A statistically significant improvement in visual acuity was detected in eyes which were treated by a laser, a combination of vitrectomy and gas tamponade or intravitreal injections of vascular endothelial growth factor inhibitors. However, the long-term effect of vascular endothelial growth factor inhibitors in treated eyes is similar to those in the control group. Conclusions: 1) Retinal arterial macroaneurysm can be suspected after clinical examination, after evaluating the fundus of patients eye, but to confirm the diagnosis fluorescein or indocyanine green angiography is required. 2) Only symptomatic retinal arterial macroaneurysms are treated. 3) Treatment of retinal arterial macroaneurysm with laser photocoagulation is appropriate and effective. 4) Treatment of retinal arterial macroaneurysm with intravitreal vascular endothelial growth factor inhibitor injections is effective and helps to improve visual acuity faster than choosing observation as primary management method. 5) Treatment of hemorrhagic retinal arterial macroaneurysms is usually chosen according to where the hemorrhage is localised. Both treatment of premacular hemorrhage with hyaloidotomy and treatment of submacular hemorrhage with vitrectomy and gas tamponade significantly improves visual acuity.
Dissertation Institution Vilniaus universitetas.
Type Master thesis
Language Lithuanian
Publication date 2022