| Abstract [eng] |
Basis in short. Bladder cancer is among the ten most common types of cancer in the world. With regard to the Lithuania’s aging population and other important risk factors and the fact that precise information is indistinguishable from the effective control of cancer, it is necessary to review the epidemiological situation of bladder cancer in Lithuania during the period from 1998 to 2015. Objective of research: to determine the morbidity of bladder cancer in accordance with stages and tendencies of its mortality, as well as relative survival rate in Lithuania during the period from 1998 to 2015. Tasks of research: 1. To assess the changes of morbidity of bladder cancer patients in accordance with the disease’s stages and overall indicators of mortality caused by bladder cancer in Lithuania during the period from 1998 to 2015. 2. To determine changes in age according to sex. 3. To assess overall tendencies of mortality caused by bladder cancer in Lithuania during the period from 1998 to 2015 according to sex. 4. To determine indicators of relative survival rate of bladder cancer during the period from 1998 to 2015 according to stage and compare the differences of survival rates of stages 0 and I. 5. To determine overall indicators of survival rate of bladder cancer patients in accordance with sex. Methods of research. Data from Lithuanian Cancer Registry register were used to perform the analysis of morbidity, mortality and relative survival rate. For the assessment of morbidity and mortality indicators, standardized indicators were calculated, and JointPoint program was used to determine the change in tendencies. Ederer II method was applied for calculations of relative survival rate. Results of research. The analysis of change points of morbidity during the period from 1998 to 2015 has shown an important growth in morbidity of stages 0, I and unknown stages of bladder cancer, as well as the decrease in II, III and IV stages. The highest increase in morbidity of both sexes is of stage 0 and the highest decrease in of stage III, according to the age group of men aged 0–44 and women aged 45–59. The research has also revealed an important change in indicators of morbidity of bladder cancer of all stages in the age groups of men aged 60–74 and 75+. In general, bladder cancer is most common in men aged 70–74 (19%) and women aged 75–79 (19.7%). There are no important tendencies in mortality caused by bladder cancer seen in the analysis of change according to sex. Relative survival rate of bladder cancer during the period of five years, measured during the period from 1998 to 2015, with regard to the stage of the disease, is decreasing, and having compared the relative survival rate of bladder cancer of stages 0 or I during the period of five years, the difference obtained was 15.59%. Relative survival rate of women within the period of five years is 57.96% and the one of men is 56.22%. Conclusion of research. The morbidity of bladder cancer during the period from 1998 to 2015 is increasing, the indicators of mortality are relatively invariable and the relative survival rate during the period of five years, with regard to the stage of the disease, is decreasing. Keywords: bladder cancer, morbidity, mortality, relative survival, trends. |
