Abstract [eng] |
The aim of this paper is to review, systemize and evaluate articles, published in scientific literature, describing COVID-19 disease and it’s treatment-related eye damage, to summarize results and to provide an important and relevant information about SARS-CoV-2 virus and it’s interface with human’s eye. Scientific literature research was applied, using Medline(Pubmed) and Google Scholar data bases. Papers where selected using keywords: COVID-19, SARS-CoV-2, ophthalmic manifestations. Coronaviruses’ spike protein has the ability to bind an Angiotenzin converting enzyme 2 which is located in various organs (eyes included) and acts like gates for a virus to get inside the cell. Virus can directly or indirectly cause conjunctivitis, keratoconjunctivitis, episcleritis, uveitis, mucormycosis, acute corneaal transplant rejection, orbital cellulitis, Adie’s pupil, Miller Fisher syndrome, optic perineuritis and other neurophthalmic complications. The most common COVID-19 related eye symptom – eye dryeness, the most commonn disease – conjunctivitis. Virus can get into the eye in various ways: by droplets transmission, aerosol transmission, hand to eye contact, nosocomial, retrograde and blood borne transmission. From the eye, the virus can get into the other parts of the body. Since ophthalmologists rarely are directly involved into the treatment of COVID-19, it is important for directly involved health care providers to properly recognize eye damage, so that appropriate treatmet would be prescribed. In addition, it is very important to use eye protection, since there is a possibility for a virus not only to cause eye disease, but also to get into deeper parts of the body through the eye. |