Title The impact of diet on acne /
Translation of Title The Impact of Diet on Acne.
Authors Bahramsari, Yashar
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Pages 30
Keywords [eng] “acne” AND “diet”, “nutrition”, “food”, “IGF-1”, “mTORC”, “glycemic index / load”, “dairy”, “chocolate”, “Mediterranean”, “fish”, “whey”, “vitamins”, “probiotics”, “BMI”
Abstract [eng] Background: Despite a high populational prevalence of acne, emerging studies and self–perceived societal belief on a relationship between western diet and acne, the topic remains controversial. To date, no dietary recommendations have been involved in current guidelines on the management of acne. Objective: The aim of this research work is to analyze the impact of diet on acne. Methods: A narrative review was conducted using recent evidence of the PubMed database, focusing on human studies from the last ten years (2012 – 2022). Results: Insulinotropic western diet enhances insulin-like growth factor-1 mediated activation of mammalian target of rapamycin complex, thereby increasing sebum production and keratinization involved in the pathogenesis of acne. A significant association between acne and consumption of food high in glycemic load, dairy products, whey protein and chocolate as well as an abnormal lipid profile was observed. A relationship between acne and BMI as well as adiponectin levels remains controversial. Consumption of a Mediterranean diet that is low in glycemic load and high in polyunsaturated fatty acids and maintenance of sufficient micronutrient levels are protective factors against the onset of acne. First research results on probiotics promise positive effects on acne, but more in vivo human studies should be performed in the future. Conclusion: Diet has a significant impact on acne and therefore, dietary recommendations should be added to the current guidelines. However, more research with high-quality evidence has to be conducted in the future.
Dissertation Institution Vilniaus universitetas.
Type Master thesis
Language English
Publication date 2022