Keywords [eng] |
Myomas in pregnancy Myomas, uterine fibroids, leiomyomas Risk factors, prevalence Complications, adverse effects, outcomes Treatment, Myomectomy, surgical techniques |
Abstract [eng] |
Background: Uterine myomas are the most common pelvic tumor in women, causing these monoclonal tumors of the myometrium to play a role in women’s health leading to a significant health care burden. A high prevalence of reproduction age in women raises concerns about infertility, adverse pregnancy outcomes obstetrical complications. Aim: This literature review aims to explore and investigate the prevalence of myomas, risk factors for the development of these tumors, effects on fertility and implantation, mainly focusing on myomas during pregnancy as well as fetal outcomes, along with the management and treatment of myomas, reviewing and providing a narrative approach of the current literature. Literature selection strategy: established mainly through the search on electronic databases such as PubMed and others. Disease mechanism: analyzing the pathogenesis and mechanisms of uterine myomas as well as pregnancy-related disease mechanisms. Clinical description: myoma growth during pregnancy, adverse pregnancy outcomes such as miscarriage, increased risk for cesarean section, placental abruption, placenta previa, premature rupture of membranes, fetal malpresentation, postpartum hemorrhage, and fetal outcomes such as preterm delivery and small for gestational age has been observed. Treatment methods: myomectomy before pregnancy and its effects on future pregnancies and myomectomy during cesarean section. Conclusion: important to identify the patient group at risk, further studies are needed to understand the clinical significance of the growth pattern and the relationship to adverse pregnancy outcomes. When discussing treatment further randomized controlled trials are needed. |