| Abstract [eng] |
Aim: Currently there is no approved gold standard in diagnosis of non-compaction cardiomyopathy. The aim of this study was to analyse diagnostic criteria of non-compaction cardiomyopathy available in magnetic resonance imaging, compare their sensitivity and specificity as well as identify strategies to improve the diagnostics of non-compaction cardiomyopathy. Methods and results: Studies were sourced from “Pubmed” database. Seven studies in English reporting on non-compaction cardiomyopathy magnetic resonance diagnostic criteria (were deemed eligible) and were included in this study. The comparison of magnetic resonance diagnostic criteria was done using sensitivity and specificity values reported by authors. Stacey et al. diagnostic criterion was not included in this comparison due to lack of reported data. The results of this literature review showed that the most sensitive (100 percent) and specific (100 percent) diagnostic criterion was reported by Captur et al. where the maximal apical fractal dimension higher than 1,30 was measured using fractal analysis performing the measurement in end-diastolic short-axis magnetic resonance frame. Conclusions: Modern magnetic resonance diagnostic criteria of non-compaction are not specific enough to discriminate physiological hypertrabeculation from non-compaction cardiomyopathy which leads to overdiagnosis of non-compaction cardiomyopthy in general population. For more accurate evaluation of non-compaction cardiomyopathy diagnostic criteria, multicenter, large cohort studies are required. Late gadolinium enhancement in cardiac magnetic resonance imaging, left ventricular function assessment, and genetic tests could further aid clinically significant diagnosis of non-compaction cardiomyopathy. |
