Abstract [eng] |
The global prevalence of viral hepatitis is very high and is increasing rapidly over the years. The infection affects pregnant women by causing maternal and perinatal morbidity and mortality. There are five liver-specific viruses (hepatitis A, B, C, D, E), each with unique epidemiology, risk of complications and response to antiviral treatment. A multidisciplinary approach to the management of viral hepatitis in pregnancy is essential in order to reduce mortality, morbidity and need for liver transplantation, it involves screening, treatment, immunoprophylaxis, various prevention techniques and encouragement of safe breastfeeding. The prevention of mother-to-child transmission is key to reducing the global burden of chronic viral hepatitis, and prevention strategies must include local healthcare and socioeconomic challenges. This literature review summarises the etiology, epidemiology, prevalence, clinical manifestation, management and mother-to-child prevention of viral hepatitis A, B, and C. A scientific review of 55 publications was performed. Articles were selected using PubMed, UpToDate and Google Scholar databases. The review includes publications in English. Also, we present a case report of a pregnant woman infected with hepatitis B, C, human immunodeficiency virus and tuberculosis. |