| Abstract [eng] |
Background: Influenza is an acute viral disease of the upper respiratory tract that is particularly dangerous for pregnant women and newborns. Due to changes in the immune system, heart and lungs, pregnant women are more likely to suffer from flu complications compared to the general population. Influenza can cause dangerous diseases such as pneumonia, damage to the heart and blood vessels. Influenza is also associated with adverse effects of pregnancy and fetus, such as premature birth, miscarriage, fetal death. Infants younger than six months are more likely to be hospitalized for viral pneumonia. Objective: To review the influenza virus effects on the outcome of pregnant women and fetus, to evaluate the safety and efficacy of antiviral treatment and to assess the benefit-risk of vaccination. Methods: Literature review based on PubMed, Medline, Web of Science scientific databases. A total of 100 articles were found, of which 80 articles were analyzed using the following inclusion criteria: publications in English over the last 15 years, keywords were used influenza, pregnancy, vaccine, antiviral therapy, consequences. Conclusions: Pregnant women are at higher risk of complications from the virus infection. Antiviral treatment is safe and should be given immediately. Vaccination against influenza should be recommended in all pregnant women, because it is safe and effective and reduces morbidity and mortality in both women and fetal. |
