| Abstract [eng] |
Leydig cell ovarian tumours are rare ovarian steroid cell neoplasms. More than 50 percent of patients are concerned with virilization symptoms such as, alopecia, hirsutism, acne and the typical changes in the voice due to the increased production of testosterone. In the report a clinical case is presented where a 71 year old woman was concerned with alopecia and an increased testosterone level in the blood. During an endocrinologist consultation these findings led to further clinical examination and diagnosis of a Leydig cell tumour of the right ovary. After undergoing a computed tomography scan there were no significant changes obtained in the ovaries. However, during a gynecologist consultation a transvaginal ultrasound scan was done to further examine the patient. The findings included an increase of the size of both ovaries and a solid mass of 21 mm diameter in the right ovary. In order to obtain a precise diagnosis a magnetic resonance imaging scan of the pelvis was performed. The results of the scan were non-homogeneous solid masses by the ovaries and the accessory glands. The size of the founded mass on the right was 21 x 19 mm, on the left - 23 x 18 mm. Due to the suspicion of a possibility of Leydig cell tumours being present in both ovaries, a bilateral laparoscopic salpingo-oophorectomy was performed. After the surgery the histopathological analysis was conducted. As a result, the diagnosis of a Leydig cell tumour in the right ovary and Leydig cell hyperplasia in the left ovary was confirmed. After the surgical treatment, the hair loss of the patient significantly decreased. In addition, normal testosterone serum levels were obtained. |
