| Abstract [eng] |
During the synthesis, carbonate hydroxyapatite, calcium-deficient hydroxyapatite, and magnesium whitlockite were synthesized by the dissolution-precipitation method using different starting materials. During the experiment, the optimal reaction temperature and duration time were selected. The synthesis of all compounds was performed at temperatures varying up to 80 ° C and atmospheric pressure. Calcium carbonate hydroxyapatite was synthesized using two different starting materials: monetite and brushite. Also, carbonate hydroxyapatite and magnesium whitlockite were synthesized using three different starting materials: monetite, brushite and gibbs. Then the obtained products were analyzed for purity and crystallinity. The initial reagent was found to have a significant effect on the purity of the products obtained, as was the reaction time. The most suitable starting reagent for calcium carbonate hydroxyapatite is brushite within a temperature of 50 °C, when pure calcium-deficient hydroxyapatite needs to be obtained using monetite at a temperature of 80 °C. The most suitable starting material for magnesium whitlockite can be used for both brushite and gibbs, and in this synthesis, Mg(CH3COO)2 ∙ 4 H2O performs a very important role, because the right amount of these materials allows to control the purity of whitlockite. In order to analyze the samples, an X-ray diffraction analysis, Fourier transform infrared spectroscopy, and scanning electron microscopy were used. These syntheses can be used to synthesize controlled-release, phase-pure compounds of carbonate hydroxyapatite, deficient hydroxyapatite and whitlockite. |
