| Abstract [eng] |
The Study on Antimicrobial Resistance of Community-Acquired Staphylococcus Aureus Strains The aim of this study was to find out the carriage rate of S. aureus in adults of Vilnius city population, to estimate the resistance to antimicrobials of isolated strains and to assess risk factors for S. aureus carriage. Goals were to identify the carriage rate of adults of Vilnius city population, to examine the resistance of S. aureus strains to antimicrobials and to assess risk factors for S. aureus carriage. Methods. To complete goals participants conducted a questionnaire about themselves and then swabs from their noses and throats were taken. Overall, 373 participants participated in this study. After extracting a pure culture, identifaction tests were performed, and S. aureus strains were identified. Using disk diffusion and minimal inhibitory concentration methods, resistance to antimicrobials were estimated. Results. The carriage rate of S. aureus among adults in Vilnius city was 36,7 %. Overall, 137 fenotypical different strains were detected. 57,7 % of strains were resistant to penicillin, 2,2 % to erythromycin, 0,7 % to tetracycline. No MRSA strains were found. Statistically significance risk factors for carriage of S. aureus were identified. They are male gender (OR = 1,86, CI 95 proc. 1,04–3,34, p = 0,031) and a usage of antimicrobials (OR = 1,61, CI 95 proc. 1,03–2,51, p = 0,031) Conclusions. Adults of Vilnius city community has a 36,7% carriage rate of Staphylococcus aureus. Extracted S. aureus strains were susceptible to cefoxitin, oxacillin, ciprofloxacin, gentamicin, norfloxacin, rifampicin and vancomycin. The highest resistance level was detected for penicillin. Male gender and the usage of antimicrobials were stastistically singnificant risk factors for S. aureus colonization. |
