| Abstract [eng] |
Background. As our population ages, the increasing incidence of non-melanoma skin cancer presents significant financial and logistical challenges. Around 90% of all cases are initiated by UV light exposure. Non-melanoma skin cancer includes squamous cell carcinoma and basal cell carcinoma, in addition to many uncommon tumors. Aim. The aim of this article is to review and analyze scientific publications, including indications and different treatment options for non-melanoma skin cancer. Materials and methods. A search of scientific articles was performed in PubMed, UpToDate, and Google Scholar databases using the terms “non-melanoma skin cancer”, “white skin cancer” and “management” or “treatment”. Articles were included if they were in English and no more than 10 years. Finally, 21 articles in all were analyzed. Results. One of the most common types of cancer in the world is skin cancer, with non-melanoma skin cancer being the most common form. Management options are operative treatment, chemical destruction, physical destruction, and immunomodulatory therapy. Photodynamic treatment and several topical medications offers promise for superficial basal cell carcinoma. Nowadays photodynamic treatment provides better cosmetic results compared to surgery. Conclusions. Non-melanoma skin cancers are generally considered treatable, but their increasing incidence has led to a growing global health problem. More and more advanced non-melanoma skin cancers are being treated with immunotherapy. Despite the development of innovative non-surgical therapies, surgical excision remains the most commonly used treatment option for non-melanoma skin cancers. |
