Title Prevalence and trends of contact sensitization in patients with psoriasis in Lithuania /
Authors Rudzikaitė-Fergizė, Gabija ; Senulytė, Augustė ; Guobytė, Neringa ; Jurėnas, Andrius ; Macejevska, Monika Marta ; Grigaitienė, Jūratė
DOI 10.1016/j.jdin.2024.02.015
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Is Part of JAAD international.. Amsterdam : Elsevier Inc.. 2024, vol. 16, p. 59-65.. ISSN 2666-3287
Keywords [eng] allergen ; contact sensitization ; cutaneous allergy ; European Baseline Series ; prevalence ; psoriasis
Abstract [eng] Background Psoriasis and allergic contact dermatitis are 2 very common dermatoses. The relationship between them has not yet been fully understood. Contact dermatitis can be an additional cause of epidermal disruption in psoriasis patients, resulting in poor management of the disease. Objective To analyze the tendencies of contact sensitization in a cohort of psoriasis patients with suspected allergic contact dermatitis. Methods Psoriasis patients (n = 85) with suspected contact dermatitis underwent patch testing with European Baseline allergen series S-1000 in Vilnius University Hospital Santaros Klinikos Centre of Dermatovenereology from August 2020 to August 2021. Their results are presented in this study. Results The patch test was positive in 43.5% (n = 37) of patients. Contact sensitization was more prevalent in patients with mild psoriasis, as characterized by Psoriasis Area Surface Index scores ≤10, compared to those with moderate-to-severe psoriasis (P < .05). Generalized psoriasis and nail involvement were more common among nonsensitized patients (P < .05). Most common contact allergens among sensitized patients were nickel (II) sulfate, formaldehyde, and potassium dichromate. Conclusion An inverse trend was observed between psoriasis severity and contact sensitization. Extended psoriatic involvement was uncommon in sensitized patients.
Published Amsterdam : Elsevier Inc
Type Journal article
Language English
Publication date 2024
CC license CC license description