Title |
Pheochromocytoma induced reverse Takotsubo cardiomyopathy: literature review / |
Authors |
Bubulytė, Silvija ; Maneikienė, Vytė Valerija |
DOI |
10.53453/ms.2024.5.20 |
Full Text |
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Is Part of |
Medicinos mokslai = Journal of medical sciences.. Kaunas : VšĮ Lietuvos sveikatos mokslinių tyrimų centras. 2024, vol. 12, iss. 3, p. 185-192.. eISSN 2345-0592 |
Keywords [eng] |
pheochromocytoma ; pheochromocytoma induced Takotsubo cardiomyopathy ; Takotsubo cardiomyopathy ; stress cardiomyopathy. |
Abstract [eng] |
Background. Pheochromocytoma is a rare endocrine tumor that principally secretes catecholamines, the amounts which can potentially cause life-threatening cardiovascular complications. A myriad of symptoms and clinical findings are associated with pheochromocytoma, including a Takotsubo cardiomyopathy. Aim. The aim was to review the recent literature on the presentation, treatment and outcomes of Takotsubo cardiomyopathy induced by catecholamines producing adrenal tumor pheochromocytoma. Methods. The article search was made using PubMed and Google Scholar databases for full-text original articles or reviews using the keywords: „pheochromocytoma“, „myocardial stunning“, „Takotsubo cardiomyopathy“, „Takotsubo syndrome“, „stress cardiomyopathy“ and their combinations. The results of primary literature search were filtered and duplicates were removed. In all, 41 publications were included in this article. Results. Due to secretion of catecholamines patients typically present with classic triade – headache, palpitation and sweating. Clinical expression may involve various cardiovascular manifestations, most usually – hypertension. Echocardiography, ventriculography can confirm takotsubo cardiomyopathy diagnosis, while computed tomography and magnetic resonance imaging – endocrine origin of pathology and laboratory urinalysis for catecholamines metabolites could prove the diagnosis of pheochromocytoma. Conclusions. Early suspicion and diagnosis of pheochromocytoma in case of cardiomyopathy or heart failure with symptoms of catecholamine excess and surgical intervention are crucial and may prevent from irreversible cardiac injury and death. |
Published |
Kaunas : VšĮ Lietuvos sveikatos mokslinių tyrimų centras |
Type |
Journal article |
Language |
English |
Publication date |
2024 |
CC license |
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