Title Comparison of general and combined anesthesia during laparoscopic colorectal surgery /
Translation of Title Bendrosios ir kombinuotos anestezijos metodų palyginimas pacientams, kuriems atliekamos storosios žarnos laparoskopinės operacijos.
Authors Gasiūnaitė, Diana
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Pages 54
Keywords [eng] laparoscopic colorectal surgery ; epidural analgesia ; combined anesthesia ; cortisol level ; stress response
Abstract [eng] The doctoral dissertation analyses and compares general endotracheal and combined endotracheal epidural anesthesia’s impact on organ systems and describes the systems parameters in laparoscopic colorectal surgery. Comparing two perioperative analgesia techniques used in laparoscopic colorectal surgery the hemodynamic and respiratory parameters trends; the impact of anesthesia and postoperative analgesia methods on patients’ tracheal extubation time, intestinal motility recovery rate, duration of hospitalization and inflammatory response have been determined. Laparoscopic colorectal resection, even being a minimally invasive technique for laparoscopic surgery, stimulates the body's response to stress and pro-inflammatory mediator’s secretion. Perioperative pain management may also influence the immune response. The doctoral dissertation analyses the impact of epidural analgesia method on the body stress response, investigating variations of cortisol and interleukin-6 levels. The results showed that analgesia and patient satisfaction using epidural analgesia method for perioperative pain management were better. Tracheal extubation time was significantly shorter. Recovery of intestinal motility using epidural analgesia was significant and much prior than using intravenous analgesia. The use of epidural analgesia in laparoscopic colorectal surgery caused less stress response – less cortisol levels increase. It has not showed the increase in number of complications.
Type Summaries of doctoral thesis
Language English
Publication date 2013