| Title |
Ligonių, kuriems atlikta širdies persodinimo operacija, kraujo T limfocitų membranos žymenų CD16/56, CD103, CD134 ekspresijos pokyčiai / |
| Translation of Title |
Variation of peripheral blood t lymphocyte cd16/56, cd103, cd134 membrane markers expression in patients after heart transplantation. |
| Authors |
Bumblauskaitė, Jurga |
| Full Text |
|
| Pages |
45 |
| Abstract [eng] |
The ame of this work was to evaluate the changes of the expresion of T lymphocyte CD16/56, CD103, CD134 surface markers in the blood of the patients who underwent heart transplantation. For this purpose we collected heparinized blood samples of 21 patients with cardiac transplant and 29 healthy volunteers. 9 patients out of 21 underwent acute cardiac transplant rejection. Blood samples of these patients were tested using flow cytometry 10 days before heart rejection and on the day when rejection was uphold. Our results showed that the expresion of T lymphocyte CD16/56 surface molecule is higher on the rejection day then in controle group. Exspresion of CD103 marker is higher 10 days before rjection than on the rejection day and is lower then in healthy volunteers. Expresion of CD134 marker is higher before transplant rejection and higher then in healthy controles. Monitoring of CD3+CD103+ and CD+CD134+ cells in the blood after heart transplantation could be helpful in prediction of heart transplant rejection. |
| Type |
Master thesis |
| Language |
Lithuanian |
| Publication date |
2011 |
