Title Autoimuninės uždegiminės reumatinės ligos ir skiepijimo tikslingumas /
Translation of Title Autoimmune inflammatory rheumatic diseases and benefit of vaccination.
Authors Arštikytė, Inesa ; Kaplerytė, Giedrė ; Butrimienė, Irena
DOI 10.5200/sm-hs.2014.121
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Is Part of Sveikatos mokslai.. Association of Lithuanian Serials (Publications). 2014, 24, 6, p. 100-104.. ISSN 1392-6373
Keywords [eng] autoimmune inflammatory rheumatic diseases ; vaccination ; vaccines
Abstract [eng] There are twenty eight infections, which might be prevented by vaccination [1]. Lithuania’s National vaccination program started in 1992, and the calendar for children prophylactic vaccination was approved in 2007. At this moment, the important question is about vaccination in adults [2]. The usefulness of vaccinations in adult patients at increased risk are the basic issue. It should be identified which adult patients are at increased risk of contracting infections, which vaccines could be used for these patients and when vaccination should be administered. Patients with autoimmune inflammatory rheumatic diseases (AIIRD) are at increased risk of contracting infections. They areprone to more serious infections and infectious complications causing significant morbidity and mortality. In patients with rheumatoid arthritis (RA), the incidence of severe infections is estimated to be twofold greater than that in general population; in patients with systemic lupus erythematosus (SLE) infections may be responsible for almost 25 proc. of all deaths.The increased susceptibility to infection can be due to: comorbidities, immunosuppressive effect of underlying autoimmune inflammatory process; the effect of immunomodulatory medication with diseasemodifying antirheumatic drugs (DMARDs), glucocorticoids and/or biologic agents. Moreover, the efficacy of vaccination in patients with AIIRD may be reduced and there is a potential risk of flares of underlying diseases after vaccination. Our aim is to evaluate, discuss and present recommendations for vaccination in patients with AIIRD to work group of Lithuanian specialists which is preparing recommendations for vaccination in adult patients with increased risk of contracting infections as found in the literature review and The European League Against Rheumatism (EULAR) recommendations for vaccination in patients with AIIRD.
Published Association of Lithuanian Serials (Publications)
Type Journal article
Language Lithuanian
Publication date 2014