| Abstract [eng] |
Advancements in dentistry continually result in innovative materials and treatment methods, which are quickly integrated into clinical practice. One of which is hydraulic calcium silicate-based root canal filling materials. However, even minor alterations in the composition of these materials can significantly affect their properties and ultimately impact clinical outcomes. Therefore, there is a growing need for an independent and thorough analysis of these materials. This study focuses on new-generation flowable hydraulic calcium silicate-based materials and their ability to improve the quality of root canal filling. Through accurate three-dimensional micro-computed tomography analysis, this study aimed to compare these materials to primary dental cement while maintaining similar biological properties. The first part of the study delves into the radiographic three-dimensional analysis of the root canal fillings based on the operators' clinical experience. Also, various root canal filling quality factors, including the total porosity of the filling material and the distribution of open and closed pores, were assessed by applying the single-cone root canal obturation technique with calcium silicate-based sealers/fillers. Additionally, the impact of ultrasonic activation on root canal filling quality and its influence on specific clinical steps was evaluated. The second part of the study focuses on the biological properties of the new generation of flowable hydraulic calcium silicate-based cements, particularly in relation to human dental pulp stem cells. The study highlights the importance of analysing freshly mixed hydraulic calcium silicate-based cements and their leachate effect on cell proliferation, morphology, and viability. In conclusion, this research yields significant and reproducible findings on hydraulic calcium silicate-based dental materials, establishing their practical usage and providing evidence-based recommendations. By scrutinizing these materials, we can potentially enhance future research and clinical protocols for dental practitioners, thereby improving the quality of root canal filling and leading to better clinical outcomes for patients. |
