| Title |
Hide-and-seek with spindle-cell-component-poor metaplastic thymoma |
| Authors |
Ražanskienė, Gintarė ; Landsbergis, Vilhelmas ; Bertašius, Vytenis ; Norvilas, Rimvydas ; Mickys, Ugnius |
| DOI |
10.7759/cureus.60136 |
| Full Text |
|
| Is Part of |
Cureus.. London : Springer Nature. 2024, vol. 16, iss. 5, art. no. e60136, p. [1-6].. ISSN 2168-8184 |
| Keywords [eng] |
islet-1 ; metaplastic thymoma ; paraneoplastic syndrome ; psoriasis ; yap1::maml2 |
| Abstract [eng] |
Metaplastic thymoma is a rare biphasic thymic tumor with indolent behavior and recurrent YAP1::MAML2 gene rearrangement. Although the diagnosis of this tumor is usually straightforward based on hematoxylin and eosin (H&E) findings alone, cases with scant spindle-cell ("pseudosarcomatous stroma") components can be easily confused with more commonly occurring type A thymoma. We present a case of metaplastic thymoma with a sparse stroma-like spindle-cell component, discussing its histological and immunohistochemical hints and drawing attention to the visual similarity to type A thymoma. This is also the first published case of metaplastic thymoma with associated psoriasis. |
| Published |
London : Springer Nature |
| Type |
Journal article |
| Language |
English |
| Publication date |
2024 |
| CC license |
|
