Title Associations between vitamin D, bone mineral density and physical performance in the elderly, and relationship of VDR gene BsmI polymorphism with severe postmenopausal osteoporosis /
Translation of Title Senyvo amžiaus žmonių vitamino D, kaulų mineralų tankio ir fizinio pajėgumo sąsajos bei VDR geno BsmI polimorfizmo ryšys su sunkia pomenopauzine osteoporoze.
Authors Strazdienė, Vaidilė
Full Text Download
Pages 40
Keywords [eng] Vitamin D ; physical performance ; the elderly ; vitamin D receptor gene
Abstract [eng] There is conflicting evidence as to whether vitamin D deficiency contributes to physical performance and muscle mass. Many studies have shown that the heritability of bone mineral density and other determinants of low-trauma bone fracture risk, but there is lack of data on specific genetic polymorphism effect. The aim of this study was to investigate association between vitamin D, bone mineral density, muscle mass, physical performance, falls and and evaluate VDR gene molecular and genetic polymorphism in the elderly. We examined 392 aged 60 years and older persons. Serum 25-hydroxyvitamin D (25(OH)D) was measured by fully automated electrochemical luminescence immunoassay method.
Type Summaries of doctoral thesis
Language English
Publication date 2013