| Abstract [eng] |
Introduction. Endoscopic ultrasound-guided fine needle biopsy has emerged as a significant advancement in diagnostic methods. Accurate diagnosis of gastroenterological conditions via minimally invasive techniques is crucial for guiding treatment and predicting outcomes. Aim. To analyze endoscopic ultrasound-guided fine needle biopsies performed in Vilnius University Hospital Santaros Klinikos in 2021-2023 and to determine the diagnostic accuracy of this method for gastroenterological pathologies. Methods. It was a retrospective study. A total of 36 fine needle biopsies were performed at Vilnius University Hospital Santaros Klinikos, Center of Hepatology, Gastroenterology, and Dietetics between February 2021 and October 2023. During the procedures, gastroenterological pathology was identified, and lesions were sampled via a fine needle using fanning and slow-pull techniques. The acquired tissue was evaluated with the MOSE technique and examined histologically. The location of the lesion, the number of needle passes, and the size of the pathology measured with endoscopic ultrasound and computed tomography image were evaluated during the upper endoscopy examination and illness course after the fine needle biopsy procedure, and histological results of the fine needle biopsy were documented. Results. Endoscopic ultrasound-guided fine needle biopsy was diagnostic in 25 of 36 patients (69.4%; 95% CI 58.7-84.1, p=0.019; χ2= 5.45). The sensitivity (81%), specificity (100%), diagnostic yield (69%), and diagnostic accuracy (85.3%) were calculated. The diagnostic accuracy was the highest when examining subepithelial lesions and reached 92.3%, and decreased when examining pancreatic lesions, reaching only 77.8%. Only the size measured on endoscopic ultrasound was statistically significant for the diagnostic accuracy of the procedure (p=0.04). Conclusions. Our research data are the first in Lithuania to describe the results of this method. Pooled data of all gastrointestinal lesions reached a diagnostic accuracy of 85.3%. The appropriate diagnostic accuracy has been achieved for subepithelial lesions, but the diagnosis of pancreatic pathology via this technique is still not sufficiently accurate. |
