Title Miomektomija: įtaka pastojimui ir nėštumui ateityje /
Translation of Title Myomectomy: conception and pregnancy outcomes.
Authors Ruočkienė, Evita
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Pages 41
Abstract [eng] The aim of research work: to evaluate the impact of hysteroscopic, laparoscopic and open myomectomy on conception, pregnancy and birth by analysing the recent scientific literature. Materials and methods: MEDLINE, CENTRAL, Wiley Online Library databases were searched. Using the PRISMA selection strategy, 9 publications were included in the systematic review: 5 on the impact of laparoscopic and laparotomic and 4 on the impact of hysteroscopic myomectomy in relation to obstetric outcomes. The articles were analysed and relevant information was described, such as the characteristics of the studies and myomas, the outcomes of pregnancies and deliveries and obstetric complications. Results: The analysis of 5 studies on laparoscopic and laparotomic myomectomy found that these interventions significantly improved the chances of conception (p < 0.001), reduced the risk of miscarriage (p < 0.001), the rate of natural births (p < 0.001) and increased the risk of preterm birth (p < 0.001). No statistical significance was found for other complications, such as uterine rupture and placental abnormalities (p = 0.0582). An analysis of 4 studies on hysteroscopic myomectomy found that hysteroscopic myomectomy significantly improved the chances of conception (p < 0.001) and reduced the risk of miscarriage (p = 0.00006). Other complications, such as caesarean section (p = 0.0646) and preterm birth (p = 0.7411), were not statistically significant. Conclusions: Myomectomy is the safest and most effective treatment for myomas in women seeking fertility preservation. This intervention improves the chances of conception, but laparoscopic and laparotomic myomectomy increases the risk of caesarean section and preterm delivery.
Dissertation Institution Vilniaus universitetas.
Type Master thesis
Language Lithuanian
Publication date 2024