| Abstract [eng] |
Background: Dental implants are one of the best ways to restore lost teeth. However, their successful osseointegration is crucial for long-term successful results. Patients who are suffering from osteoporosis and are receiving medications for this disease may face potential failure risks in terms of osseointegration and long-term success. Objectives: This extended literature review aims to investigate the impact of osteoporosis medications, especially antiresorptive drugs, on the success rate of dental implants. Methods: Electronic searches were performed from September 2023 to December 2023 for “oral implant” OR “dental implant” AND (antiresorptive drugs OR bisphosphonates OR denosumab OR osteoporosis treatment were performed using PubMed, Scopus, ResearchGate, Ovid, and ScienceDirect. Time restrictions were applied and included the years from 2010-2024. Manual searches were conducted to supplement the digital searches in the following scientific journals: Journal of Osseointegration and Journal of the Endocrine Society. Results: A total of 17 studies were included, which met the eligibility criteria. The studies assessed dental implants' success/failure rate in patients suffering from osteoporosis who underwent treatment for this disease before and/or during implant placement. At present, the literature review did not find a difference in the success rate of dental implants in patients who are or have been undergoing medical treatment for osteoporosis compared to healthy patients. Hormonal therapies seem to influence peri-implant bone loss but do not significantly impact the overall implant success rate. The use of blood products can be recommended to support the healing phase and to lower the risk of possible complications. There is a lack of a widely accepted consensus regarding implant success criteria, which is needed to facilitate further research and to allow an accurate comparison of the results. Conclusion: Within the limits of the study, the literature review did not find a difference in the success rate of dental implants in patients who are or have been undergoing medical treatment for osteoporosis compared to healthy patients. More extensive clinical trials, longer follow-up times, detailed success criteria, and surgical techniques are recommended to understand further and investigate the associated risks of osteoporosis medications on dental implantation. |
