| Title |
The relationship between diabetes mellitus and periodontitis / |
| Translation of Title |
The Relationship Between Diabetes Mellitus and Periodontitis. |
| Authors |
Guettler, Justus |
| Full Text |
|
| Pages |
53 |
| Keywords [eng] |
Diabetes, Periodontitis, Diabetes and periodontitis relations, dysbiotic shift, hyperglycemia, chronic inflammation, lifestyle modifications. |
| Abstract [eng] |
Diabetes mellitus and Periodontitis are two of the most common chronic diseases worldwide. As they co-occur frequently in the same patient and exacerbate each other, a precise understanding of their pathogenesis is needed for their management and prevention. Many aspects in the association of their pathogenesis still remain unclear. Further, the awareness of the concomitant occurrence is low amongst patients and clinicians. The research question of this Master thesis is "How do Diabetes mellitus and Periodontitis interact with each other and why?". The research strategy was a research literature review of the available research literature. Key findings are that Diabetes mellitus induces chronic inflammation via its characteristic hyperglycemia, oxidative stress and immune cell stimulation. Periodontitis is a chronic inflammation of the periodontium and has systemic effects via inducing an oral dysbiosis and an altered systemic inflammatory response. Key findings of this thesis are that Diabetes mellitus exacerbates periodontitis by an altered and impaired immune response, oxidative stress and microvascular changes in the periodontal tissues amongst other tissues. Periodontitis vice versa exacerbates Diabetes mellitus by an altered immunological Response and the formation of insulin resistance. The key Management is that both diseases can be easily avoided by lifestyle Management, sports, proper oral hygiene and smoking cessation. |
| Dissertation Institution |
Vilniaus universitetas. |
| Type |
Master thesis |
| Language |
English |
| Publication date |
2024 |
