| Abstract [eng] |
Mammary Paget's disease is a rare form of breast cancer that is commonly misdiagnosed, resulting in a prolonged diagnostic process, leading to poorer prognosis and higher mortality rates. This narrative literature review comprehensively reviews the epidemiology, risk factors, clinical presentations, differential diagnosis, diagnostic procedures, treatment modalities, and prognosis associated with Mammary Paget's disease. Mammary Paget's disease of the breast is primarily observed in the presence of ductal carcinoma in situ or invasive ductal carcinomas. Nevertheless, Paget's disease of the breast may occur without underlying carcinoma. Due to the wide variability of clinical presentation and the similarity to many common skin diseases, diagnosing Mammary Paget ́s disease remains challenging for clinicians, and the condition can be overlooked or misdiagnosed easily. This thesis discusses the newest clinical studies and data regarding diagnostic peculiarities, treatment, and prognosis of Mammary Paget's disease of the breast. Furthermore, this review summarizes recent research on the subject, including biopsy changes, pathogenesis, treatment, and prognosis. Prompt diagnosis and intervention are crucial in improving treatment outcomes. This review aims to create awareness of this rare disease, especially indicating the importance of early diagnosis to improve the prognosis of Patients diagnosed with this disease. |
