Title Differential diagnosis of secondary hypertension: literature review and clinical case analysis /
Translation of Title Differential Diagnosis of Secondary Hypertension: Literature Review and Clinical Case Analysis.
Authors Katzenstein, Macarena
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Pages 27
Keywords [eng] Secondary hypertension, polymorbidity, airway obstruction, nasal polyp, cardiovascular disease, diagnostic strategies, personalized medicine.
Abstract [eng] This thesis will delve into the complexities of accurately diagnosing secondary hypertension through a literature review and a detailed clinical case study. The clinical case centers on a 61-year-old male with significant cardiovascular and renal comorbidities, who struggled with persistent, treatment-resistant nocturnal hypertension. Traditional treatment methods were proven ineffective, prompting further, in-depth diagnostic exploration. The further diagnostic work-up led to the discovery and subsequent surgical excision of a large nasal polyp, which had been obstructing the patient's airway to the epiglottis. The excision led to a notable decrease in the patient’s average systolic blood pressure by 20 mmHg. This thesis delves into the complexities of diagnosing secondary hypertension, highlighting the critical role of atypical factors such as airway obstructions in its aetiology and management. It integrates insights from Rossi et al.'s "Practice Recommendations for Diagnosis and Treatment of the Most Common Forms of Secondary Hypertension" with findings from the NIH resource on the multifaceted causes and consequences of secondary hypertension. This synthesis emphasizes the global imperative for precise diagnosis and underscores persistent challenges in preventive strategies for cardiovascular health. Through this comprehensive examination, the thesis advocates for customized diagnostic approaches that enhance patient outcomes and contribute significantly to the evolution of personalized medicine, highlighting the essential nature of thorough diagnostic evaluations in managing complex cases of secondary hypertension.
Dissertation Institution Vilniaus universitetas.
Type Master thesis
Language English
Publication date 2024